Mura delle Grazie was part of the sixth, or rather penultimate, city wall, built before 1630. This wall surrounded the city within the perimeter of its historical centre.

The walls stretched from Porta di San Tomaso in the direction of Carbonara and Castelletto, then descended towards Acquasola; from Carignano the line wounds towards the sea, literally creating a watershed with the City, right under the Oratories of S. Antonio, S. Giacomo Maggiore and the church of Nostra Signora delle Grazie.

From here, the walls continued towards the Molo area, running along the Malapaga prisons until they reached Porta Siberia.After the urban sprawl of the 19th century, only a few parts of this 16th-century wall still exist today.

One of these parts is the so-called Acquasola 'knight', the other is evidenced by the Malapaga walls at the Molo, but the longest and most impressive one is definitely the remaining part of Mura delle Grazie. A small great wall stretching for over four hundred metres, in the section between the Church of Nostra Signora delle Grazie and the remains of the old Marina in Via Madre di Dio.